In a statement, his agent said, “Bob is now looking forward to his retirement with his family, and would greatly appreciate that his privacy be respected at this time.

"He wishes to thank all the great and brilliant people he has worked with over the years, and all of his fans who have supported him during a wonderful career.”

The 69-year-old Hoskins has had a successful career spanning four decades, with seveal hits following his breakthrough in 80s gangster flick The Long Good Friday, alongside Helen Mirren and a pre-fame Pierce Brosnan.

Golden Globe nominations came for 1988’s part-animated Who Framed Roger Rabbit, and 2005’s Mrs Henderson Presents. He is also well known for his roles in Mona Lisa, Hook, Mermaids and Last Orders. His most recent film role was as a dwarf in Snow White And The Huntsman.

Recently, he’s also found renewed success on television, winning an International Emmy for his role in Jimmy McGovern’s The Street.

Mr Hoskins was born in Bury St Edmonds, and began acting in the late 60s. He started getting regular television work in the 70s, before film work began later in that decade.

127,000 people in the UK currently suffer from Parkinson’s disease.